1. Guan R and Mariuzza RA. (2007) Peptidoglycan recognition proteins of the innate immune system. Trends Microbiol. In press.

2. Fernandez MM, Guan R*, Swaminathan CP, Malchiodi EL, Mariuzza RA. (2006) Crystal structure of staphylococcal enterotoxin I (SEI) in complex with MHC-II molecule DR1/HA. J. Biol. Chem. 281, 25356-64. (*Co-first authorship).

3. Guan R, Brown PH, Swaminathan CP, Roychowdhury A, Boons G-J, and Mariuzza RA. (2006) Crystal structure of human peptidoglycan recognition protein Ia bound to a muramyl pentapeptide from Gram-positive bacteria. Protein Science, 15, 1199-1206.

4. He XL, Guan R*, Zhang Y, Wang DC. (2006) A dimeric structure of the scorpion toxin BmK M1 at 1.4 angstrom resolution: Non-proline cis peptide bond and its intrinsic structural elements. Prog. Biochem. & Biophys. 33: 231-239. (*Co-first authorship)

5. Natarajan K, Hicks A, Mans J, Robinson H, Guan R, Mariuzza RA, and Margulies DH. (2006) Crystal Structure of the Murine Cytomegalovirus MHC-I Homolog m144. J. Mol. Biol. 358, 157-171.

6. Swaminathan CP, Brown PH, Roychowdhury A, Wang Q, Guan R, Silverman N, Goldman WE, Boons G-J, and Mariuzza RA. (2006) Dual strategies for peptidoglycan discrimination by peptidoglycan recognition proteins (PGRPs). Proc. Natl. Acad. Sci. U S A. 103, 684-689.

7. Guan R, Roychowdhury A, Ember B, Kumar S, Boons G-J and Mariuzza RA. (2005) Crystal structure of a peptidoglycan recognition protein (PGRP) in complex with peptidoglycan. J. of Endotoxin Research, 11, 41-46.

8. Cho S, Swaminathan CP, Yang J, Kerzic MC, Guan R, Kieke MC, Kranz DM, Mariuzza RA, and Sundberg EJ. (2005) Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction. Structure (Camb) 13, 1775-1787.

9. Guan R, Wang Q, Sundberg EJ, and Roy Mariuzza. (2005) Crystal Structure of Human Peptidoglycan Recognition Protein S (PGRP-S). J. Mol. Biol. 347, 683-691.

10. Kumar S, Roychowdhury A, Ember B, Wang Q, Guan R, Mariuzza RA and Boons G-J. (2005) Selective Recognition of Synthetic Gram-Positive and Negative Peptidoglycan Fragments By Human Pgrp-S And Pgrp-Ia. J. Biol. Chem. 280, 37005-37012.

11. Li C, Guan R, Xiang Y, Zhang Y, and Wang D. (2005) Structure of an excitatory insect-specific toxin with an analgesic effect on mammals from the scorpion Buthus martensii Karsch. Acta Cryst. D61, 14-21.

12. Guan R, Roychowdhury A, Ember B, Kumar S, Boons G-J, and Mariuzza RA. (2004) Structural basis for peptidoglycan binding by peptidoglycan recognition proteins. Proc. Natl. Acad. Sci. U S A. 101, 17168-17173.

13. Guan R, Xiang Y, He X, Wang C, Wang M, Zhang Y, Sundberg EJ, and Wang D. (2004) Structural mechanism governing cis and trans isomeric states and an intramolecular switch for cis/trans isomerization of a non-proline peptide bond observed in crystal structures of scorpion toxins. J. Mol. Biol. 341, 1189-1204.

14. Guan R, Malchiodi EL, Wang Q, Schuck P, and Mariuzza RA. (2004) Crystal structure of the C-terminal peptidoglycan-binding domain of human peptidoglycan recognition protein Ia. J Biol. Chem. 279, 31873-31882.

15. Dam R, Guan R*, Natarajan K, Dimasi N, Chlewicki LK, Kranz DM, Schuck P, Margulies DH, and Mariuzza RA. (2003) Variable MHC class I engagement by Ly49 natural killer cell receptors demonstrated by the crystal structure of Ly49C bound to H-2Kb. Nature Immunology. 4, 1213-1222. (*Co-first authorship)

16. Yang J, Swaminathan CP, Huang Y, Guan R, Cho S, Kieke MC, Kranz, DM, Mariuzza RA, and Sundberg EJ.（2003）Dissecting cooperative and additive binding energetics in the affinity maturation pathway of a protein-protein interface. J Biol Chem. 278, 50412-50421.

17. Guan R, He X, Wang M, Xiang Y, Li G, and Wang D. (2002) Purification, crystallization and initial structural solution of a new alpha-like toxin with cardiac toxicity from scorpion Buthus martensii Karsch.  Protein Pept Lett. 9, 441-449.

18. Guan R, Xiang Y, Wang M, Li G, and Wang D. (2001) Crystallization and preliminary X-ray analyses of a depressant insect toxin from scorpion Buthus martensii Karsch. Acta Cryst. D57, 1313-1315.

19. Guan R, Wang M, and Wang D. (2001) Crystallization with detergents for some soluble proteins. J. Crystal Growth 231, 273-279.

20. Guan R, Wang M, and Wang D. (2001) A depressant insect toxin with analgesic effect from scorpion Buthus martensii Karsch. Biochimica et Biophysica Acta 1549, 9-18.

21. Guan R, Wang M, Wang D, and Wang D. (2001) A new analgesic peptide with insect-specific toxicity from scorpion Buthus martensii Karsch: Purification and charaterization. J. Pept. Res. 58, 27-35.

22. Guan R, Zheng J, Hu Z, and Wang D. (2000) Crystallization and preliminary X-ray analysis of the thermostable sweet protein mabinlin II. Acta Cryst. D56, 918-919.

23. Guan R, Liu X, Liu B, Wang M, and Wang D. (2000) Crystallization and preliminary X-ray analyses of insect neurotoxins with analgesic effect from scorpion Buthus martensii Karsch. Acta Cryst. D56, 1012-1014.

24. Guan R, Wang M, Liu X, and Wang D. (2000) Crystallization and preliminary X-ray analysis of an anti-insect toxin BmK I6 from Buthus martensii Karsch scorpion. Chinese Science Bulletin 45, 1489-1492.